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What kind of nano-objects are we talking about?
It is necessary to distinguish natural and "anthropogenic" (related to human activities) nano-objects. Either they are unintentional (combustion, abrasion, processes emitting dust,…) or manufactured. Recent toxicology studies show that some synthesized nano-objects will likely reveal toxic for some forms or chemical compositions. So we must take appropriate precaution measures.
The incident unintentional anthropogenic particles produced by combustion or an industrial process are well known. We must now take into account the specifically engineered nano-objects.
Inventory of nanoparticle concentrations according to different activities [S. Singh et al., International Journal of Nanotechnology and Nanomedecine 1 (2016)].